A heart that had stopped beating for 20 minutes was transplanted at Niguarda Hospital in Milan. This is a donation defined as "heart-stopped". The heart was harvested and transplanted by the Cardiac Surgery and Heart Transplantation team at Niguarda Hospital in Milan, directed by Claudio Russo. Liver and kidneys were also taken from the deceased man and later transplanted to other facilities in the National Transplant Network. The donation took place at the ASST Sette Laghi Circolo Hospital in Varese and involved the team of the General Intensive Care Unit and Heart Care Unit (which belongs to the Cardiovascular Department) directed by Luca Cabrini and Paolo Severgnini, respectively, and the Hospital Procurement Coordination Unit directed by Federica De Min. This type of donation and transplantation is innovative in that the heart is restarted through extracorporeal circulation techniques that are put in place after death in subjects in whom intensive treatments are discontinued as a result of very severe neuro lesions. Italian regulations require twenty minutes of no cardiac activity for the determination of the subject's death. Until a year ago, this time was considered inconsistent with the resumption of heart activity. Instead, the procedures implemented in this case allowed its transplantation and functional recovery.