Given the current state of "geopolitical instability, fueled by unresolved crises in Eastern Europe and the Middle East, along with inflationary pressures and trade tensions, the Italy-United States relationship is more important than ever" , with Italy able to play a "key role, of balance and mediation, between Europe and the USA". According to Stefano Lucchini, head of the American Chamber of Commerce in Italy (AmCham), the relationship between the two countries has "never been so relevant". And this concept was reiterated in all of the speeches delivered during the 110th assembly of the institution, which is affiliated with the Chamber of Commerce of Washington D.C., a network of 117 American chambers of commerce that are present in 103 countries and have over 3 million member companies. The transatlantic relationship is "the most important in the world," emphasized Simone Crolla, managing director of AmCham: "it accounts for one-third of global GDP. 64% of investments in the US come from Europe, whereas 56% of US investments go to Europe," he added. In this context, Italy is one of the primary partners of the United States, which is the country's second largest export market after Germany, with a value of 76.3 billion dollars in 2024, and the leading country in terms of trade surplus, with around $44 billion. The United States is also one of Italy's largest foreign investors, with an FDI value of 29 billion dollars in 2023 (up 25.7% from 2003 and +13.4% from 2022).