A 14.5% drop among men and 5% among women: this is the decline in cancer mortality in Italy between 2020 and 2025. The nation is at the forefront of the survival rankings following a cancer diagnosis, and this is not limited to the European average (-3.5% for males and -1.2% for women) during the same period. Italy outperforms France (-10.4% and -2.8%), Germany (-9.5% and -8.1%), and Spain (-7.7% and -1.8%), to mention a few other countries in similar situations. The National Health Service is functioning properly. However, in order to continue down this path and provide the best treatment possible for all, skilled personnel and resources are required. Data collection, particularly analysis, is critical to understanding the dismal situation: it is anticipated that in 2025, roughly 1,280,000 people would die from cancer in the European Union, with 176,000 in Italy. However, preventive measures are important. Adopting a healthy lifestyle helps prevent 40% of all cancers. As a result, it is critical to focus on primary prevention, screening programs, and therapeutic breakthroughs.