Eating healthy also involves communicating with your DNA. Many natural substances contained in common meals, including green tea, broccoli, turmeric, red wine, and soy, can reprogram gene expression. This can help to minimize inflammation, boost antioxidant defenses, and preserve a youthful biological age. This is validated by an international study led by the University of Padua and published in the journal "Advances in Nutrition", one of the most prestigious in the field of nutrition. As a result, some foods include chemicals capable of modifying the epigenetic mechanisms that regulate gene expression, hence influencing aging and chronic disease prevention. The article systematically collects and analyzes over one hundred experimental and clinical studies that show how bioactive compounds found in food, such as polyphenols, isothiocyanates, folates, catechins, and curcumin, can modulate the activity of DNA methyltransferases (DNMTs), which are key enzymes in DNA methylation processes. These enzymes regulate gene activation and deactivation, controlling how the body responds to environmental stress, inflammation, and aging. "The objective is to comprehend the potential of diet to impede or prevent the biological processes that contribute to chronic diseases and aging, thereby facilitating the development of nutrition that is more personalized and evidence-based", stated Sofia Pavanello, the study's leader.