The Department of Engineering and Geology at Gabriele d'Annunzio University of Chieti-Pescara executed the world's inaugural test on a full-scale 3D-printed structure. The test was conducted on a shaking table, a large-scale equipment that replicated the action of a 7.2 magnitude earthquake (Kefalonia, 1953) with up to 200% (40 shakings). Synthetic accelerograms were employed to conduct a seismic qualification (30 shakes) until structural damage occurred. The objective was to induce structural failure in order to identify the primary damage mechanisms and evaluate its exceptional resistance capacity. The tests enabled the collection of a vast and useful dataset, which included high-resolution instrumental measurements and contactless technologies. The study, undertaken as part of the European ERIES (Engineering Research Infrastructures for European Synergies) project and supported by the Horizon Europe program—an initiative that facilitates transnational access to exemplary experimental infrastructures in the domain of structural and seismic engineering—was carried out in collaboration with the University of Bristol, which supplied its 6x4 meter shaking table, the University of Porto, Asdea s.r.l., and HTL.tech. The d'Annunzio research received the prestigious "Best Paper Award" at the 20th ANIDIS 2025 Conference—the leading Italian Earthquake Engineering Conference—for its high methodological rigor and significant impact on the scientific and technical community, outperforming over 300 submitted papers. "Globally," explained Professor Valentino Sangiorgio, "there are approximately 200 3D-printed buildings, predominantly located in the United States and China, with three prototypes in Italy. In Europe, the most significant cluster is in Dublin, where these structures are mainly used for public housing projects. Although numerous companies have already commenced construction using this technology, the seismic performance of 3D-printed structures has yet to be empirically tested. 'D'Annunzio' has taken a crucial initial step toward establishing standardized materials and providing valuable insights for legislative innovation in the domain of earthquake-resistant construction".