In late 15th-century Florence, Sandro Botticelli and his workshop developed one of their most successful models: the Madonna holding the Child, flanked by the young Saint John the Baptist. This image, destined for long-term success in Botticelli's workshop, has been revived and reinvented over time, and it is once again in the spotlight on the international market. The work, painted in tempera and oil on panel, will be one of the highlights of Christie's Old Masters sale in New York on February 4, 2026, with an estimated value of $4-6 million. The panel depicts the Virgin seated at a lectern as she embraces the Christ Child, who tenderly presses his cheek against hers. Mary is dressed in a scarlet robe beneath a blue cloak with a green lining, elegantly trimmed with gold; her long blond braids are veiled by a diaphanous, lace-edged cloth. The Child, clothed in a silk garment with gilded trim, gazes at his mother. To the left, Saint John the Baptist, wearing his traditional camel-hair tunic and a vivid crimson mantle, pays homage to his cousin. The composition is rooted in one of Botticelli’s early Madonnas, Madonna and Child with the Young Saint John, now housed at the Louvre and dated to around 1468. Sandro Botticelli’s market is uneven, but marked by exceptional peaks when major works come to light. Emblematic is the sale of Young Man Holding a Roundel, which fetched $92.2 million at Sotheby’s in 2021, setting an all-time record for the artist.