The Spanish Grand Prix saw Ducati return to victory thanks to Alex Marquez, who won at the Jerez circuit, replicating his previous year's win. The Gresini rider claimed the lead in the opening laps, capitalizing on his brother Marc's fall after starting from pole position.
Marco Bezzecchi finished second behind Marquez, extending his championship lead, and Fabio Di Giannantonio finished third after a strong race. The race was full of surprising twists and turns, including Francesco Bagnaia's retirement and difficulties for some expected participants. Aprilia, however, delivered a strong overall performance, placing four bikes in the top positions. In the overall standings, Bezzecchi strengthens his advantage over Jorge Martin, while Di Giannantonio moves up to third. The championship remains highly competitive, with open balances and several riders capable of contending for top positions.