An innovative biopesticide that is capable of combating the insect "enemies" of bees and hives without compromising human health or the environment. As part of the RNApi initiative, a team of ENEA researchers at the Trisaia Research Center (Matera), led by entomologist Salvatore Arpaia, is currently in the process of developing it. A unique molecule has been created that functions as a targeted "switch": it identifies a critical gene in the small hive beetle, Aethina tumida, and "silences" it, thereby preventing the production of a protein that is essential for its growth and development. This method allows for pest management without injuring bees. The early findings, published in the Springer-Nature group's Journal of Pest Science, pave the door for the application of breakthrough green biotechnologies to safeguard bees, who are valuable "sentinels of biodiversity". Aethina tumida is an invasive species endemic to Sub-Saharan Africa that harms European honeybee colonies by feeding on beeswax, eggs, and larvae, making the honey acidic. Following its discovery in Calabria in 2014, the insect was designated as an invasive alien species of concern in the European Union, where it continues to be a problem. Its recent migration from mainland Italy to Sicily, with verified infestations in apiaries in the province of Messina, highlights the importance of efficient containment in limiting its territorial growth.