On the centenary of World Mission Sunday, Rome, the beating heart of the Catholic Church and seat of the papacy, has issued a powerful plea for unity and care for the most vulnerable. In a moving video message published by the Vatican, Pope Leo traced his personal and ecclesiastical roots, recalling how the faithful's prayers accompanied his youth and vocation as Augustinian missionaries, later providing physical support for his pastoral ministry in Peru. The Pontiff expressed profound gratitude for the historic support for this anniversary, underscoring the central theme of this centennial milestone, "One in Christ, united in mission". In keeping with the Italian Catholic tradition, which regards the Pope as a global spiritual director and a point of reference for international solidarity efforts, the message highlights the significance of Baptism as a summons to collective commitment. Thus, the Holy Father's invitation resonates beyond the confines of Italy: to unite as a single universal family to provide concrete support, hope, and comfort to those in need, with a particular emphasis on the most disadvantaged and marginalized individuals in this world.